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Working with a trusted practitioner is essential to weigh these factors, assess individual tolerance, and establish boundaries around dosage and duration

Taken together, the abundance of marker genera in healthy and inflammation-associated oral microbiomes reaffirms the potential impact of smokeless tobacco consumption in the dysbiosis of oral microbiome ( Figure 7 )

However, the observed associations between vaping and subsequent cigarette smoking do not necessarily indicate a causal "gateway effect", as shared social, behavioral, or genetic risk factors may contribute to both behaviors

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The Office for National Statistics (ONS) figures show that there are about 6.6 million adult cigarette smokers in the United Kingdom